Thromboprophylactic low-molecular-weight heparin versus standard of care in unvaccinated, at-risk outpatients with COVID-19 (ETHIC): an open-label, multicentre, randomised, controlled, phase 3b trialClinical Trial Published on 2022-08-012022-10-05 Journal: The Lancet. Haematology [Category] Coronavirus, Fulltext, MERS, 임상, [키워드] 1:1 105 patient 105 patients adverse event adverse events all-cause mortality analysed Asian assigned Belgium benefit black bleeding event Brazil Clinical practice Complete country COVID-19 COVID-19 vaccine death died dose Efficacy and safety eligibility eligible participant enrolled enrolment evaluate event rate FIVE Follow-up had no hazard ratio hospitalisation hospitalised in both group increased risk India Inflammation intention-to-treat population International IQR main analysis men middle multicentre no difference non-critically ill patient one patient Open-label Outpatient participant Patient patients with COVID-19 Pneumonia primary efficacy endpoint Prophylactic Prophylaxis random randomisation randomised Randomly receive Registered risk factor Safety Safety Monitoring Board Sanofi severe disease severity Sex similar studies South Africa Spain Standard of care Standard-of-care symptom onset symptomatic thromboembolic complications Trial uterine bleeding was done weighed were assessed white with COVID-19 women [DOI] 10.1016/S2352-3026(22)00173-9 PMC 바로가기 [Article Type] Clinical Trial
Structural conservation among variants of the SARS-CoV-2 spike postfusion bundleSARS-CoV-2 스파이크 후 융합 번들의 변종 간의 구조적 보존Article Published on 2022-04-192022-09-11 Journal: Proceedings of the National Academy of Sciences of [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alter antiviral inhibitor antiviral inhibitors assembly change coronavirus COVID-19 COVID-19 vaccine COVID-19 vaccines cryo-EM cryogenic electron microscopy determine domain eight functional glycoprotein heptad repeat host cell HR1HR2 Interaction local effect membrane fusion membrane fusion. Microscopy molecular monoclonal antibody mutant Mutation mutations Nostoc omicron Omicron variant postfusion related viruses reported resulting SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants selected severe acute respiratory syndrome Coronavirus similar studies similar study spike glycoprotein Structure structures target the SARS-CoV-2 therapy trimeric variant variants of SARS-CoV-2 Viral RNA viral spike wild-type [DOI] 10.1073/pnas.2119467119 PMC 바로가기 [Article Type] Article
A new threshold reveals the uncertainty about the effect of school opening on diffusion of Covid-19새로운 문턱은 개학이 Covid-19의 확산에 미치는 영향에 대한 불확실성을 나타냅니다.Article Published on 2022-02-222022-09-10 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] Affect Analysis Applied mathematics Awareness children choice compartmental model computation conducted Course COVID-19 pandemic Data collection data-driven diffusion Effect Epidemiology feature implication lockdowns mathematical Mathematics and computing open outbreak pandemic phase transition Phase transitions and critical phenomena reason reason for reveal School Schools similar studies Specific subpopulation subpopulations threshold transmission rate transmission rates Vaccinations variant variants [DOI] 10.1038/s41598-022-06540-w PMC 바로가기 [Article Type] Article
Skin manifestations in patients with COVID-19: a prospective observational study during the first wave of the pandemic in the UK and review of the recent literatureObservational Study Published on 2022-02-012022-10-05 Journal: European journal of dermatology : EJD [Category] COVID19(2023년), SARS, 임상, [키워드] abnormality analysed changes Coagulation conducted COVID-19 Dermatology described determine Effect England Epidemiology First wave form heterogeneous hospital hypercoagulability identify infected with COVID-19 lesion livedoid manifestation Manifestations material mechanism nasopharyngeal organ system pandemic pathophysiology Patient patients PCR swab positive Prevalence prospective observational study required Research SARS-CoV-2 similar studies skin lesion skin manifestation total patient United Kingdom university variable variety viral infection with COVID-19 [DOI] 10.1684/ejd.2022.4202 PMC 바로가기 [Article Type] Observational Study
Vaccine-associated complications: a comparative multicenter evaluation among dental practitioners and dental students—which candidate vaccine is more safe in SARS COV II, Gam-COVID-Vac (Sputnik V), ChAdOx1 nCoV-19 (AstraZeneca), BBV152 (Covaxin), or BBIBP-CorV(Sinopharm)?Research Published on 2022-01-132022-10-30 Journal: Maxillofacial Plastic and Reconstructive Surgery [Category] COVID-19, [키워드] acute respiratory syndrome adverse effects adverse event age analyses AstraZeneca BBIBP-CorV candidate vaccine ChAdOx1 nCoV-19 clinical assessment conducted coronavirus dental practitioner EBV evaluate fatigue Frequency Gam-COVID-Vac individual Infection Influenza injection local pain majority malaise MERS multicenter Pain platform provoking questionnaire reaction reported Result retained risk Safe sample sizes SARS-CoV2 SARSCoV-2 Side effect Side effects Side-effect similar studies Sinopharm supplementary material Symptom systemic side effects vaccination Vaccine vaccine administration [DOI] 10.1186/s40902-021-00330-6 PMC 바로가기 [Article Type] Research
A longitudinal study of anti-SARS-CoV-2 antibody seroprevalence in a random sample of the general population in Hiroshima in 20202020년 히로시마의 일반 인구 무작위 표본에서 항 SARS-CoV-2 항체 혈청 유병률에 대한 종단 연구Article Published on 2022-01-012022-09-11 Journal: Environmental health and preventive medicine [Category] SARS, 진단, 치료기술, [키워드] 95% confidence interval anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody Antibody test asymptomatic infection asymptomatic infections asymptomatic patient asymptomatic patients calculated changes in conducted confirmed COVID-19 case COVID-19 vaccine determine FIVE General population Hiroshima immunoassay immunoassays Japan longitudinal study Ministry of Health participant positive Prevalence random Random sample Random sampling reagent SARS-CoV-2 SARS-COV-2 infection Seroconversion seroconversion. Seroprevalence similar studies similar study stratified stratified random sample was selected Welfare [DOI] 10.1265/ehpm.22-00016 PMC 바로가기 [Article Type] Article
Distinguishing gene flow between malaria parasite populations말라리아 기생충 집단 사이의 유전자 흐름을 구별합니다Research Article Published on 2021-12-202022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Analysis analyzed approach complementary conditions connectivity death descent disease disease control disperse distinguishing drug-resistant effort epidemiological evaluate gene flow Genetic genetic marker Genetic markers genomic Genomic surveillance geographic location geographic locations Guidance identity implementation implication include Infection information interpretability Interpretation Local malaria malaria control malaria parasite malaria parasites Metrics Migration Multiple National observation observations P. falciparum parasite Population populations public health question sampling sequence similar studies Spread strain Surveillance understanding whole genome sequence [DOI] 10.1371/journal.pgen.1009335 PMC 바로가기 [Article Type] Research Article
COVID-19-related institutional betrayal associated with trauma symptoms among undergraduate studentsResearch Article Published on 2021-10-202022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] avoidance correlated COVID-19 COVID-19 infection COVID-19 pandemic dependent on distress examined Gender Health Healthcare systems individual outcome Prevalence PROTECT reduce remained Research significantly similar studies Symptom trauma United State [DOI] 10.1371/journal.pone.0258294 PMC 바로가기 [Article Type] Research Article
Automatic detection of COVID-19 using pruned GLCM-Based texture features and LDCRF classification정리된 GLCM 기반 텍스처 기능 및 LDCRF 분류를 사용하여 COVID-19 자동 감지Article Published on 2021-10-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 진단, 치료기술, [키워드] Accuracy adaptive applied assist Automatic automatic detection average CAD chest X-ray co-occurrence computer-aided detection COVID-19 COVID-19 test Cross-validation CXR dataset diagnostic effective feature Features GLCM-Based texture features IMPROVE input Latent-dynamic conditional random fields lung lung tissue median Non-COVID-19 normalized physician poor quality practitioners Precision radiological Radiological images. random recall reduce Region reported researcher ROI ROIs similar studies similar study tested threshold value [DOI] 10.1016/j.compbiomed.2021.104781 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Antibody Testing in Health Care Workers: A Comparison of the Clinical Performance of Three Commercially Available Antibody Assays의료 종사자의 SARS-CoV-2 항체 검사: 상업적으로 이용 가능한 3가지 항체 분석의 임상 성능 비교Comparative Study Published on 2021-09-292022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] 95% CI 95% confidence interval Abbott Abbott Architect SARS-CoV-2 IgG acute respiratory syndrome acute respiratory syndrome coronavirus anti-SARS-CoV-2 anti-spike antibody antibody antibody assays SARS-CoV-2 Asian assays blood sample Blood samples Care choice clinical coronavirus correlated COVID-19 infection COVID-19 pandemic COVID-19 serological assays demonstrated detected antibody Diagnosis distance Elecsys ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay Ethnicity Factor functional HCW Health Health care help IgG Immunity Immunoglobulin Immunoglobulin G indicate Infection infections male natural infection Odds ratio PCR PCR-confirmed PCR-confirmed COVID-19 performance positive public health respiratory retained Roche Roche Elecsys SARS-CoV-2 panantibody sample selection SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 serological assay SARS-CoV-2 seroprevalence sensitivity Serological assay serological response Seronegativity Seroprevalence serum sample serum samples severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe symptoms Sex significant difference significant differences significantly similar studies study period subset symptom severity tested Testing the timing [DOI] 10.1128/Spectrum.00391-21 PMC 바로가기 [Article Type] Comparative Study